Primary Identifier | MGI:1914293 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 67043 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including TORC2 signaling; cellular response to epidermal growth factor stimulus; and positive regulation of fat cell differentiation. Located in several cellular components, including growth cone; perikaryon; and synaptic membrane. Is expressed in central nervous system; lower jaw incisor; and upper jaw incisor. Orthologous to human SYAP1 (synapse associated protein 1). PHENOTYPE: Male chimeras hemizygous for a gene trapped allele appear normal at E9.5. Mice hemizygous or homozygous for a knock-out allele are viable and fertile with no overt defects in adult brain morphology and cultured motoneuron survival or axon growth. Hemizygous KO males display reduced advanced locomotor skills. [provided by MGI curators] |