Primary Identifier | MGI:95836 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 14829 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables neuropeptide receptor activity. Involved in several processes, including positive regulation of behavioral fear response; positive regulation of respiratory gaseous exchange; and psychomotor behavior. Acts upstream of or within regulation of cell population proliferation. Located in plasma membrane. Is expressed in dentate gyrus subgranular zone; lung; lung epithelium; lung mesenchyme; and small intestine epithelium. Orthologous to human GRPR (gastrin releasing peptide receptor). PHENOTYPE: Male mice hemizygous for a knock-out allele lack bombesin-induced satiety response. Male mice hemizygous for another knock-out allele exhibit hyperactivity, abnormal social investigation, and insensitivity to gastrin-releasing peptide-induced hypothermia. [provided by MGI curators] |