| Primary Identifier | MGI:3042378 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 333605 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in positive regulation of synapse structural plasticity and postsynaptic actin cytoskeleton organization. Is active in glutamatergic synapse and postsynaptic density. Is expressed in dorsal root ganglion; facial ganglion; lateral ventricle choroid plexus; metencephalon part of 4th ventricle choroid plexus; and trigeminal ganglion. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 104. Orthologous to human FRMPD4 (FERM and PDZ domain containing 4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased inflammation-induced pain and thermal pain in a chronic pain model. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
