| Primary Identifier | MGI:97890 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 19361 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables DNA strand exchange activity; chromatin binding activity; and single-stranded DNA binding activity. Involved in double-strand break repair involved in meiotic recombination; telomere maintenance via recombination; and telomere maintenance via telomere lengthening. Acts upstream of or within several processes, including DNA metabolic process; cellular response to hydroxyurea; and chromosome organization. Located in chromosome, telomeric region; cytoplasm; and lateral element. Is active in site of double-strand break. Is expressed in several structures, including brain; compacted morula; gonad; hemolymphoid system; and paravertebral ganglion. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group R; breast cancer; mirror movements 2; and ovarian cancer. Orthologous to human RAD51 (RAD51 recombinase). PHENOTYPE: Homozygotes for targeted null mutations die prior to implantation, usually by the eight-cell stage. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
