| Primary Identifier | MGI:1270153 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 20402 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable RNA binding activity. Predicted to be located in nuclear speck and nucleolus. Is expressed in several structures, including central nervous system; genitourinary system; gut; heart and pericardium; and musculature. Used to study amyotrophic lateral sclerosis. Orthologous to human ZNF106 (zinc finger protein 106). PHENOTYPE: Mice homozygous for a null allele exhibit an abnormal gait, progressive motor deficits, kyphosis, weight loss, severe adult-onset degenerative sensory-motor axonopathy, mitochondrial dysfunction, and premature death. [provided by MGI curators] |