| Primary Identifier | MGI:2444823 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 98396 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables inorganic cation transmembrane transporter activity. Involved in cellular response to magnesium ion and magnesium ion transmembrane transport. Predicted to be located in basolateral plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; mesenteric adipose tissue; and respiratory system. Human ortholog(s) of this gene implicated in nephronophthisis. Orthologous to human SLC41A1 (solute carrier family 41 member 1). PHENOTYPE: Homozygous null mice exhibit partial rescue of the negative effects of magnesium starvation on Krebs cycle enzyme activity in cardiac mitochondria and increased electron transport chain complex I, III, IV, and V activities but decreased complex II activity irrespective of the type of magnesium diet. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
