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Protein Coding Gene : Zfp462 zinc finger protein 462

Primary Identifier  MGI:107690 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  242466
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0)

Predicted to enable DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; ear; genitourinary system; jaw; and limb primordium. Used to study generalized anxiety disorder. Orthologous to human ZNF462 (zinc finger protein 462).
PHENOTYPE: Mice homozygous for knock-out allele exhibit complete prenatal lethality with decreased birth body size and eyelids open at birth. Heterozygotes show postnatal growth retardation, low body weight and brain weight, and anxiety-like behaviors with excessive self-grooming and hair loss. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 9430078C22 gene,
  • gene trap insertion site 4-2,
  • 9430078C22Rik,
  • Zfp462,
  • Gt4-2,
  • Zfpip,
  • zinc finger protein 462,
  • MGD-MRK-36266,
  • MGI:2443147

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Proteins

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Mouse features --> Functions (GO terms)

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