| Primary Identifier | MGI:107690 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 242466 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; ear; genitourinary system; jaw; and limb primordium. Used to study generalized anxiety disorder. Orthologous to human ZNF462 (zinc finger protein 462). PHENOTYPE: Mice homozygous for knock-out allele exhibit complete prenatal lethality with decreased birth body size and eyelids open at birth. Heterozygotes show postnatal growth retardation, low body weight and brain weight, and anxiety-like behaviors with excessive self-grooming and hair loss. [provided by MGI curators] |