Primary Identifier | MGI:2143528 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 103142 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables all-trans-retinol dehydrogenase (NAD+) activity. Acts upstream of or within 9-cis-retinoic acid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in midbrain. Orthologous to human RDH16 (retinol dehydrogenase 16). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and healthy, with no apparent alterations in tissue retinoid and serum dihydrotestosterone levels. [provided by MGI curators] |