| Primary Identifier | MGI:87991 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 11657 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables molecular carrier activity. Involved in bilirubin transport. Located in cytoplasm. Is active in extracellular region. Is expressed in several structures, including alimentary system; brain; extraembryonic component; liver and biliary system; and trunk musculature. Human ortholog(s) of this gene implicated in several diseases, including biliary tract benign neoplasm; blood protein disease; hepatobiliary system cancer (multiple); hyperthyroxinemia; and middle cerebral artery infarction. Orthologous to human ALB (albumin). PHENOTYPE: Mice homozygous for a TALEN-mediated deletion exhibit analbuminemia but appear healthy and grossly normal and breed normally. Mice heterozygotes for an ENU-induced point mutation have significantly reduced plasma albumin and calcium levels and significantly elevated alkaline phosphatase activity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
