Primary Identifier | MGI:894668 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 20706 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protease binding activity; and serine-type endopeptidase inhibitor activity. Acts upstream of or within T cell mediated cytotoxicity. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be active in cytoplasm and extracellular space. Is expressed in atrioventricular canal; atrioventricular valve; endocardial cushion; interventricular septum; and mitral valve. Orthologous to human SERPINB9 (serpin family B member 9). PHENOTYPE: Mice homozygous for a knock-out allele show reduced leukemia susceptibility following murine leukemia virus infection in specific-pathogen free conditions. [provided by MGI curators] |