| Primary Identifier | MGI:105305 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 20514 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables L-aspartate transmembrane transporter activity and neutral L-amino acid transmembrane transporter activity. Involved in L-aspartate import across plasma membrane and transport across blood-brain barrier. Located in basal plasma membrane. Is active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver; and respiratory system. Orthologous to human SLC1A5 (solute carrier family 1 member 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced B cells, CD4+ memory T cells in older mice, Th1 and Th17 T cells, susceptibility to EAE and T cell uptake of glutamine and leucine. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
