| Primary Identifier | MGI:2141917 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 101540 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable protein kinase C binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Involved in positive regulation of DNA biosynthetic process; positive regulation of interleukin-2 production; and positive regulation of signal transduction. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and vibrissa. Orthologous to human PRKD2 (protein kinase D2). PHENOTYPE: Mice homozygous for a knock-in allele exhibit impaired IgM and IgG1 antigen responses and CD4+ and CD8+ T cell production of IL2 and IFN-gamma in response to TCR stimulation. Mice homozygous for a gene trap allele exhibit normal T lymphocyte maturation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
