| Primary Identifier | MGI:101948 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 22411 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable cytokine activity; frizzled binding activity; and protein kinase activator activity. Involved in heart development. Acts upstream of or within several processes, including Wnt signaling pathway; circulatory system development; and regulation of cytokine production. Located in extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart and pericardium; and limb. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma. Orthologous to human WNT11 (Wnt family member 11). PHENOTYPE: Homozygous mutation of this gene results in extensive embryonic lethality and mutants surviving to birth die within the first 2 days of life. The kidneys are small and exhibit delayed development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
