| Primary Identifier | MGI:2142989 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 78658 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable histone binding activity. Involved in cerebral cortex development; mitotic chromosome condensation; and regulation of chromosome segregation. Acts upstream of or within meiotic chromosome separation. Located in condensed nuclear chromosome; germinal vesicle; and kinetochore. Part of condensin complex. Is expressed in cerebral cortex subventricular zone. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 22. Orthologous to human NCAPD3 (non-SMC condensin II complex subunit D3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality between implantation and somite formation. [provided by MGI curators] |