Primary Identifier | MGI:1351651 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 27377 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP-dependent peptidase activity. Involved in several processes, including mitochondrial protein processing; neuronal stem cell population maintenance; and positive regulation of mitochondrial fusion. Located in mitochondrion. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in optic atrophy 11. Orthologous to human YME1L1 (YME1 like 1 ATPase). PHENOTYPE: Homozygous null embryos die prior to E13.5, and show a developmental delay from E8.5 to E12.5. [provided by MGI curators] |