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Protein Coding Gene : Actl7a actin-like 7a

Primary Identifier  MGI:1343051 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  11470
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in acrosome assembly and fertilization. Located in acrosomal vesicle; male germ cell nucleus; and motile cilium. Colocalizes with Golgi apparatus. Human ortholog(s) of this gene implicated in male infertility and spermatogenic failure. Orthologous to human ACTL7A (actin like 7A).
PHENOTYPE: Mcie homozygous for a null allele exhibit male infertility associated with acrosomal ultrastructural defects. [provided by MGI curators]
  • synonyms:
  • actin-like 7a,
  • t-actin 2,
  • Tact2,
  • Actl7a

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For