Primary Identifier | MGI:3712553 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 627009 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to several human genes including PRAMEF20 (PRAME family member 20). PHENOTYPE: Homozygous null mice exhibit no apparent developmental or fertility defects but embryos show an increase in DNA methylation levels across the genome. [provided by MGI curators] |