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Polymorphic Pseudogene : Oas1b 2'-5' oligoadenylate synthetase 1B
Primary Identifier  MGI:97430 Organism  mouse, laboratory
Chromosome  5 Mgi Type  polymorphic pseudogene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables double-stranded RNA binding activity. Involved in negative regulation of viral genome replication and response to virus. Located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human OAS1 (2'-5'-oligoadenylate synthetase 1).
PHENOTYPE: Spontaneous mutations of this gene result in altered susceptibility to viral infection. [provided by MGI curators]
  • synonyms:
  • flavivirus resistance,
  • Mmu-L1,
  • MGI:95562,
  • Oias2,
  • 2'-5' oligoadenylate synthetase 2,
  • Oias-2,
  • L1,
  • 2'-5' oligoadenylate synthetase 1B,
  • Flv,
  • Oas1b,
  • MGD-MRK-13024,
  • Wnv,
  • MGI:2388353,
  • MGD-MRK-9840,
  • MGD-MRK-13026,
  • Flavivirus resistance,
  • West Nile virus
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

Trail: PolymorphicPseudogene

0 Strain

0 Transcripts

0 Transgenic Expressors

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





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