| Primary Identifier | MGI:1913103 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 60363 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and paracellular tight junction channel activity. Involved in paracellular transport; regulation of intestinal D-glucose absorption; and regulation of intestinal lipid absorption. Located in lateral plasma membrane and tight junction. Is expressed in intestine epithelium; lung; metanephros; pancreas; and stomach. Orthologous to human CLDN15 (claudin 15). PHENOTYPE: Mice homozygous for a knock-out allele are viable and grow normally with an enlarged upper small intestinal phenotype (megaintestine) resulting from enhanced proliferation of normal cryptic cells after weaning. [provided by MGI curators] |