| Primary Identifier | MGI:1916299 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 69049 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cysteine-S-conjugate N-acetyltransferase activity and lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Acts upstream of or within determination of left/right symmetry and heart development. Predicted to be located in Golgi apparatus; endoplasmic reticulum membrane; and endoplasmic reticulum-Golgi intermediate compartment membrane. Is expressed in brain; genitourinary system; gut; and spinal cord. Orthologous to human NAT8 (N-acetyltransferase 8 (putative)) and NAT8B (N-acetyltransferase 8B (putative, gene/pseudogene)). PHENOTYPE: Mice homozygous for an ENU-induced mutation exhibit complex congenital heart disease associated with heterotaxy, abdominal organ situs anomalies, omphalocele and gastroschisis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
