| Primary Identifier | MGI:1919200 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 71950 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity; and lysine-acetylated histone binding activity. Involved in several processes, including cell dedifferentiation; positive regulation of transcription by RNA polymerase II; and regulation of stem cell division. Acts upstream of or within several processes, including negative regulation of BMP signaling pathway; negative regulation of cell differentiation; and response to retinoic acid. Located in nucleoplasm. Is active in chromatin. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and immune system. Orthologous to several human genes including NANOG (Nanog homeobox). PHENOTYPE: Mice homozygous for a disruption in this gene die between E3.5 and E5.5 with abnormal embryonic and extraembryonic tissue development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
