| Primary Identifier | MGI:102687 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 12044 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable BH domain binding activity and channel activity. Involved in negative regulation of apoptotic process. Acts upstream of or within B cell homeostasis and negative regulation of B cell apoptotic process. Predicted to be located in cytoplasm. Predicted to be active in mitochondrial outer membrane. Is expressed in several structures, including bone; central nervous system; heart; hemolymphoid system; and respiratory system. Orthologous to human BCL2A1 (BCL2 related protein A1). PHENOTYPE: Homozygous null mutants show enhanced spontaneous apoptosis of neutrophils, while both heterozygous and homozygous null mutants lack LPS-induced neutrophil apoptosis inhibition. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
