Primary Identifier | MGI:2663985 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 280287 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable kisspeptin receptor binding activity. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; decidualization; and negative regulation of cell migration. Predicted to be located in apical plasma membrane; extracellular space; and neuronal cell body. Is expressed in diencephalon and metanephros. Used to study hypogonadotropic hypogonadism 13 with or without anosmia. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor). PHENOTYPE: Homozygote null mice are infertile with abnormal sexual maturation associated with hypogonadotropism [provided by MGI curators] |