Primary Identifier | MGI:1919282 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 57028 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables magnesium ion binding activity; protein homodimerization activity; and pyridoxal phosphatase activity. Involved in dephosphorylation; pyridoxal phosphate catabolic process; and regulation of modification of postsynaptic structure. Located in cell-cell junction. Is active in glutamatergic synapse and postsynapse. Is expressed in alimentary system; eye; limb; nervous system; and tail. Orthologous to human PDXP (pyridoxal phosphatase). PHENOTYPE: Mice homozygous for a null allele exhibit increased GABA levels, improved spatial learning and memory, mild anxiety, weakness, and abnormal amino acid metabolism in the brain. [provided by MGI curators] |