Primary Identifier | MGI:5621540 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 102643076 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in digestive tract morphogenesis and enteroendocrine cell differentiation. Is expressed in duodenum; pancreas; and stomach. Human ortholog(s) of this gene implicated in congenital diarrhea. Orthologous to human PERCC1 (proline and glutamate rich with coiled coil 1). PHENOTYPE: Mice homozygous for a null allele exhibit reduced weight, premature death, abnormal intestinal and fecal microbiome composition and reduced gastrin-expressing cells. [provided by MGI curators] |