Primary Identifier | MGI:2448355 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 15077 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in lung. Orthologous to several human genes including H3C13 (H3 clustered histone 13); H3C14 (H3 clustered histone 14); and H3C15 (H3 clustered histone 15). PHENOTYPE: A homozygous point mutation causes microphthalmia (resulting from abnormal cornea, lens and retina development), increased locomotor activity, rearing and body temperature, and decreased anxiety, body mass and blood lipid levels. [provided by MGI curators] |