| Primary Identifier | MGI:107846 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 15469 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GATOR1 complex binding activity; histone methyltransferase activity; and protein-arginine omega-N asymmetric methyltransferase activity. Involved in several processes, including RNA splicing; cellular response to methionine; and positive regulation of TORC1 signaling. Acts upstream of or within in utero embryonic development. Located in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and lung. Used to study cleft palate. Orthologous to human PRMT1 (protein arginine methyltransferase 1). PHENOTYPE: Embryos homozygous for a null mutation die before E6.5 and exhibit abnormal embryonic tissue morphology. Mice homozygous for a conditional allele activated in germ cells exhibit male infertility with azoospermia due to meiosis arrest at the leptotene or zygotene stage. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
