| Primary Identifier | MGI:3775191 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 100113365 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including chloride ion binding activity; neurexin family protein binding activity; and protein homodimerization activity. Involved in several processes, including brainstem development; social behavior; and territorial aggressive behavior. Located in plasma membrane and synapse. Is active in glycinergic synapse and postsynaptic specialization membrane. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human NLGN4X (neuroligin 4 X-linked) and NLGN4Y (neuroligin 4 Y-linked). PHENOTYPE: Homozygous mutation of this gene results in deficits in reciprocal social interaction and communication as well as small reduction of total brain and brain stem volume. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
