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Publication : Isolation and sequence of a cDNA corresponding to a src-related gene expressed in murine hemopoietic cells.

First Author  Holtzman DA Year  1987
Journal  Proc Natl Acad Sci U S A Volume  84
Issue  23 Pages  8325-9
PubMed ID  3317404 Mgi Jnum  J:8946
Mgi Id  MGI:57411 Doi  10.1073/pnas.84.23.8325
Citation  Holtzman DA, et al. (1987) Isolation and sequence of a cDNA corresponding to a src-related gene expressed in murine hemopoietic cells. Proc Natl Acad Sci U S A 84(23):8325-9
abstractText  We have isolated a murine cDNA that shares extensive homology with genes encoding the src (Rous sarcoma virus oncogene)-related family of protein-tyrosine kinases. The cDNA includes an open reading frame of 1509 base pairs, and conceptual translation predicts a protein of 56 kDa. Blot-hybridization analysis indicates that this src-related gene is expressed in normal macrophages and in cell lines representing both the myeloid and lymphoid B-cell lineages and, accordingly, is designated bmk (B cell/myeloid kinase). In addition, bmk mRNA levels increase following the induced differentiation of the murine myelomonocytic leukemic cell line WEHI-3B.
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