First Author | Ito T | Year | 2000 |
Journal | Gene | Volume | 244 |
Issue | 1-2 | Pages | 55-63 |
PubMed ID | 10689187 | Mgi Jnum | J:58248 |
Mgi Id | MGI:1346986 | Doi | 10.1016/s0378-1119(00)00007-x |
Citation | Ito T, et al. (2000) Gene structure and chromosome mapping of mouse transcription elongation factor S-II (Tcea1). Gene 244(1-2):55-63 |
abstractText | We report the organization and chromosome localization of the mouse transcription elongation factor S-II gene (Tcea1). This gene was found to be a single copy gene consisting of 10 exons spanning approximately 30kb. Its organization was the same as those of the mouse testis-specific S-II gene (Tcea2) and Xenopus general S-II gene (xTFIIS.oA), but different from that of the human S-II gene family. We also identified a processed pseudogene (Tcea1-ps1) with a sequence highly homologous to those of S-II cDNAs but containing a translation termination codon within its open reading frame. Linkage analysis showed that Tcea1 and Tcea1-ps1 are mapped on mouse chromosomes 1 and 15, respectively. Relationships between Tcea1 and S-II cDNAs isolated so far are discussed. |