| First Author | Yoshimura Y | Year | 1999 |
| Journal | Gene | Volume | 237 |
| Issue | 1 | Pages | 193-9 |
| PubMed ID | 10524250 | Mgi Jnum | J:57451 |
| Mgi Id | MGI:1344825 | Doi | 10.1016/s0378-1119(99)00287-5 |
| Citation | Yoshimura Y, et al. (1999) Genomic analysis of male germ cell-specific actin capping protein alpha. Gene 237(1):193-9 |
| abstractText | The Gsg3 gene which expresses specifically in haploid germ cells is a mouse testicular homolog of somatic cell type actin capping protein alpha (ACP alpha). We have obtained a mouse Gsg3 genomic clone using cDNA as a probe. Sequencing data showed that the Gsg3 gene was not interrupted by introns. The transcription initiation site of the gene was preceded not by a TATA box or GC rich promoter motifs, but by two consensus cAMP-response element (CRE) motifs at the putative position. Southern blotting analysis showed that Gsg3 is a single copy gene in the mouse, and conserved in mammals. Phylogenetic analysis showed that Gsg3 is a novel ACP alpha specific for haploid germ cells. |
