First Author | Swift S | Year | 1998 |
Journal | Biochim Biophys Acta | Volume | 1442 |
Issue | 2-3 | Pages | 394-8 |
PubMed ID | 9804998 | Mgi Jnum | J:50920 |
Mgi Id | MGI:1313045 | Doi | 10.1016/s0167-4781(98)00180-8 |
Citation | Swift S, et al. (1998) Structure and chromosomal mapping of the TNF-alpha inducible endothelial protein 1 (Edp1) gene in the mouse. Biochim Biophys Acta 1442(2-3):394-8 |
abstractText | EDP1 was identified as a human gene activated transcriptionally by tumour necrosis factor ex in endothelial cells. Here we have characterised the mouse Edp1 gene. We show that the gene encodes a highly conserved protein and describe its intron/exon structure. The presence of related genes in the sequence databases suggests that Edp1 is part of a gene family. Fine mapping of the gene in the mouse genome indicates that, as expected from its location on human chromosome 17, the mouse Edp1 gene maps to mouse chromosome 11. However, surprisingly, the gene does not map to the expected region of mouse chromosome 11 suggesting that a change in the order of genes has occurred within a conserved linkage group. (C) 1998 Elsevier Science B.V. All rights reserved. |