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Publication : Cloning and developmental expression of mouse aldehyde reductase (AKR1A4).

First Author  Allan D Year  2000
Journal  Mech Dev Volume  94
Issue  1-2 Pages  271-5
PubMed ID  10842086 Mgi Jnum  J:63126
Mgi Id  MGI:1860505 Doi  10.1016/s0925-4773(00)00293-8
Citation  Allan D, et al. (2000) Cloning and developmental expression of mouse aldehyde reductase (AKR1A4). Mech Dev 94(1-2):271-5
abstractText  The aldo-keto reductase superfamily catalyzes the reduction of a broad range of aldehydes and ketones to their corresponding alcohols. Here we report the cloning of the mouse aldehyde reductase cDNA and its embryonic pattern of expression. From stages E7.5 to E13.5 the gene encoding for this enzyme is expressed at high levels in several tissues, including the neural ectoderm, gut endoderm, somites, branchial arches, otic vesicles, limb buds, and tail bud. In adult mice aldehyde reductase was expressed in all tissues examined.
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