| First Author | Uetz P | Year | 1994 |
| Journal | FEBS Lett | Volume | 339 |
| Issue | 3 | Pages | 302-6 |
| PubMed ID | 8112471 | Mgi Jnum | J:16897 |
| Mgi Id | MGI:64955 | Doi | 10.1016/0014-5793(94)80435-4 |
| Citation | Uetz P, et al. (1994) Organisation of the murine 5-HT3 receptor gene and assignment to human chromosome 11. FEBS Lett 339(3):302-6 |
| abstractText | We have isolated the murine gene encoding the 5-HT3 receptor (5-HT3R), a member of the ligand-gated ion channels, that mediates a variety of physiological effects in central and peripheral neurons. DNA sequence analysis of the 5-HT3R gene revealed its organisation in 9 exons distributed over approximately 12 kbp of DNA. Alternative use of exon 9 splice acceptor sites generated two 5-HT3R variants. The 5-HT3R gene, whose structure is closely related to neuronal and muscle AChR alpha genes, as demonstrated by four common splice junctions, was localised on human chromosome 11. |
