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Publication : Nucleotide sequence of c-H-ras-1 gene from B6C3F1 mice.

First Author  Przybojewska B Year  1996
Journal  Acta Biochim Pol Volume  43
Issue  3 Pages  575-8
PubMed ID  8922043 Mgi Jnum  J:36374
Mgi Id  MGI:83807 Citation  Przybojewska B, et al. (1996) Nucleotide sequence of c-H-ras-1 gene from B6C3F1 mice. Acta Biochim Pol 43(3):575-8
abstractText  The c-H-ras-1 gene of an B6C3F1 mouse was isolated and nucleotide sequence determined. Our study has revealed that this c-H-ras-1 gene consists of four exons, separated by three introns ranging in size from 150 to 649 bp. The coding parts of the sequence of mouse c-H-ras-1 gene show no important differences as compared with those of the rat, hamster and human gene. More numerous changes were found in introns. The identity of mouse c-H-ras-1 gene with rat, hamster and human ones at the nucleotide level is 86.40%, 80.04% and 67.87%, respectively. Comparison of amino acids in protein sequence of c-H-ras gene of mouse, rat, hamster and human points to high degree of conservation of the gene.
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