First Author | Przybojewska B | Year | 1996 |
Journal | Acta Biochim Pol | Volume | 43 |
Issue | 3 | Pages | 575-8 |
PubMed ID | 8922043 | Mgi Jnum | J:36374 |
Mgi Id | MGI:83807 | Citation | Przybojewska B, et al. (1996) Nucleotide sequence of c-H-ras-1 gene from B6C3F1 mice. Acta Biochim Pol 43(3):575-8 |
abstractText | The c-H-ras-1 gene of an B6C3F1 mouse was isolated and nucleotide sequence determined. Our study has revealed that this c-H-ras-1 gene consists of four exons, separated by three introns ranging in size from 150 to 649 bp. The coding parts of the sequence of mouse c-H-ras-1 gene show no important differences as compared with those of the rat, hamster and human gene. More numerous changes were found in introns. The identity of mouse c-H-ras-1 gene with rat, hamster and human ones at the nucleotide level is 86.40%, 80.04% and 67.87%, respectively. Comparison of amino acids in protein sequence of c-H-ras gene of mouse, rat, hamster and human points to high degree of conservation of the gene. |