First Author | Oldekamp J | Year | 2004 |
Journal | Gene Expr Patterns | Volume | 4 |
Issue | 3 | Pages | 283-8 |
PubMed ID | 15053976 | Mgi Jnum | J:89169 |
Mgi Id | MGI:3038586 | Doi | 10.1016/j.modgep.2003.11.008 |
Citation | Oldekamp J, et al. (2004) Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development. Gene Expr Patterns 4(3):283-8 |
abstractText | We have characterized for the first time the mouse expression patterns of the three known members of the novel RGM gene family ('Repulsive Axonal Guidance molecules' A, B and C) by in situ hybridization. Both RGM A and B are mostly expressed in central nervous system, while RGM C is exclusively expressed in all striated muscle and in the myocardium. RGM A and B appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGM A appears in the neuroepithelium, and only RGM B in the peripheral nervous system. During development, both RGM A and B appear also in lung and in limb cartilage, while RGM B has additional expression domains in pancreas. |