| First Author | Kubo Y | Year | 1993 |
| Journal | Nature | Volume | 362 |
| Issue | 6416 | Pages | 127-33 |
| PubMed ID | 7680768 | Mgi Jnum | J:4135 |
| Mgi Id | MGI:52636 | Doi | 10.1038/362127a0 |
| Citation | Kubo Y, et al. (1993) Primary structure and functional expression of a mouse inward rectifier potassium channel [see comments]. Nature 362(6416):127-33 |
| abstractText | A complementary DNA encoding an inward rectifier K+ channel (IRK1) was isolated from a mouse macrophage cell line by expression cloning. This channel conducts inward K+ current below the K+ equilibrium potential but passes little outward K+ current. The IRK1 channel contains only two putative transmembrane segments per subunit and corresponds to the inner core structure of voltage-gated K+ channels. The IRK1 channel and an ATP-regulated K+ channel show extensive sequence similarity and constitute a new superfamily. |
