| First Author | Miyamoto H | Year | 1994 |
| Journal | Biochim Biophys Acta | Volume | 1217 |
| Issue | 3 | Pages | 312-6 |
| PubMed ID | 8148377 | Mgi Jnum | J:17595 |
| Mgi Id | MGI:65629 | Doi | 10.1016/0167-4781(94)90291-7 |
| Citation | Miyamoto H, et al. (1994) Molecular cloning of the murine homologue of CD63/ME491 and detection of its strong expression in the kidney and activated macrophages. Biochim Biophys Acta 1217(3):312-6 |
| abstractText | The mouse homologue of CD63/ME491 (Mu-CD63) was molecularly cloned and analyzed. Mu-CD63 exhibited a strikingly high similarity to CD63/ME491 and the rat homologue. Northern blot analysis revealed that Mu-CD63 mRNA was expressed strongly in the kidney of adult mice, especially in the glomerulus fraction, implying the possibility that Mu-CD63 plays an important role in maintaining normal renal function. Activated macrophages and splenocytes exhibited strong expression of Mu-CD63 mRNA, whereas cultured thymocytes barely expressed the mRNA irrespective of cell activation. Taken together, the present results suggest that Mu-CD63 expression is associated with differentiation and/or development of certain cell types, but not necessarily with cell proliferation. |
