First Author | Andrews NC | Year | 1993 |
Journal | Nature | Volume | 362 |
Issue | 6422 | Pages | 722-8 |
PubMed ID | 8469283 | Mgi Jnum | J:14933 |
Mgi Id | MGI:63085 | Doi | 10.1038/362722a0 |
Citation | Andrews NC, et al. (1993) Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. Nature 362(6422):722-8 |
abstractText | Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterized by complementary DNA cloning as a new basic region-leucine zipper protein which dimerizes with a ubiquitous partner to form native NF-E2. |