| First Author | Seaman C | Year | 2001 |
| Journal | Mech Dev | Volume | 101 |
| Issue | 1-2 | Pages | 245-8 |
| PubMed ID | 11231084 | Mgi Jnum | J:68157 |
| Mgi Id | MGI:1932197 | Doi | 10.1016/s0925-4773(00)00563-3 |
| Citation | Seaman C, et al. (2001) Netrin-3 protein is localized to the axons of motor, sensory, and sympathetic neurons. Mech Dev 101(1-2):245-8 |
| abstractText | The netrin family of axon guidance cues has been shown to play a pivotal role in the guidance of a variety of axon projections during embryonic development, both in the vertebrate and invertebrate. While the guidance potential of netrin-1 has been examined in depth in many regions of the developing mouse brain very little information is available on the expression and activity of netrin-3. Here we show that the netrin-3 protein is present on motor neurons and subpopulations of neurons within sensory and sympathetic ganglia. Moreover, significant levels of netrin-3 protein were found to be associated with the axons projecting from these neurons suggesting a role for netrin-3 in axon pathfinding and fasciculation within the peripheral nervous system. |
