| First Author | Kunieda T | Year | 2003 |
| Journal | FEBS Lett | Volume | 535 |
| Issue | 1-3 | Pages | 61-5 |
| PubMed ID | 12560079 | Mgi Jnum | J:80238 |
| Mgi Id | MGI:2445515 | Doi | 10.1016/s0014-5793(02)03858-9 |
| Citation | Kunieda T, et al. (2003) Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain(1). FEBS Lett 535(1-3):61-5 |
| abstractText | We previously identified the Mblk-1 gene in the honeybee brain, which encodes a transcription factor containing two DNA binding motifs, termed RHF1 and 2 (Takeuchi et al. (2001) Insect Mol. Biol. 121, 134-140). Here, we identified two mouse Mblk1 homologues, Mlr1 and Mlr2. Both encode proteins containing a single DNA-binding motif highly conserved with RHF2 and activate transcription mediated by a DNA element recognized by honeybee Mblk-1. Mlr1 was expressed predominantly in the spermatocytes of the testis, while Mlr2 was expressed in various tissues other than testis. Mlr1 transcripts were lost in the testis of W/W(v) mutant mice, suggesting a role in spermatogenesis. |
