| First Author | Romancino DP | Year | 2013 |
| Journal | FEBS Lett | Volume | 587 |
| Issue | 9 | Pages | 1379-84 |
| PubMed ID | 23523921 | Mgi Jnum | J:237678 |
| Mgi Id | MGI:5816441 | Doi | 10.1016/j.febslet.2013.03.012 |
| Citation | Romancino DP, et al. (2013) Identification and characterization of the nano-sized vesicles released by muscle cells. FEBS Lett 587(9):1379-84 |
| abstractText | Several cell types secrete small membranous vesicles that contain cell-specific collections of proteins, lipids, and genetic material. The function of these vesicles is to allow cell-to-cell signaling and the horizontal transfer of their cargo molecules. Here, we demonstrate that muscle cells secrete nano-sized vesicles and that their release increases during muscle differentiation. Analysis of these nanovesicles allowed us to characterize them as exosome-like particles and to define the potential role of the multifunctional protein Alix in their biogenesis. |
