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Publication : Molecular cloning and sequencing of the murine alpha-2-macroglobulin receptor cDNA.

First Author  Van Leuven F Year  1993
Journal  Biochim Biophys Acta Volume  1173
Issue  1 Pages  71-4
PubMed ID  8485155 Mgi Jnum  J:4760
Mgi Id  MGI:53242 Doi  10.1016/0167-4781(93)90244-8
Citation  Van Leuven F, et al. (1993) Molecular cloning and sequencing of the murine alpha-2-macroglobulin receptor cDNA. Biochim Biophys Acta 1173(1):71-4
abstractText  We have molecularly cloned and sequenced the mouse alpha-2-macroglobulin receptor cDNA. The cDNA contained 14849 bases with one large open reading frame of 4545 codons which is one more than in the corresponding human cDNA. Comparison of the predicted mouse and human receptor proteins revealed the very conserved nature of this receptor with an overall amino acid identity of more than 97%. A dramatic example of this is the presence of 331 cysteine residues predicted in the mouse protein, of which 327 are positionally conserved relative to human.
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