| First Author | Choi E | Year | 1983 |
| Journal | Science | Volume | 221 |
| Issue | 4607 | Pages | 283-6 |
| PubMed ID | 6407114 | Mgi Jnum | J:15354 |
| Mgi Id | MGI:63480 | Doi | 10.1126/science.6407114 |
| Citation | Choi E, et al. (1983) Murine I-A beta chain polymorphism: nucleotide sequences of three allelic I-A beta genes. Science 221(4607):283-6 |
| abstractText | The polymorphism of immune response genes plays a critical role in determining the immune capabilities of a particular individual. The molecular nature of this polymorphism was studied by examining the structure of the coding portions of three alleles of the I-A beta chain gene, an immune response gene whose protein product constitutes a subunit of the I-A molecule. Comparison of the I-A beta chains encoded by these alleles revealed an amino acid sequence divergence of 5 to 8 percent. The differences were found to be a series of short alterations clustered in the amino terminal half of the polypeptide. |
