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Publication : Spatial pattern of receptor expression in the olfactory epithelium.

First Author  Nef P Year  1992
Journal  Proc Natl Acad Sci U S A Volume  89
Issue  19 Pages  8948-52
PubMed ID  1384038 Mgi Jnum  J:30467
Mgi Id  MGI:77977 Doi  10.1073/pnas.89.19.8948
Citation  Nef P, et al. (1992) Spatial pattern of receptor expression in the olfactory epithelium. Proc Natl Acad Sci U S A 89(19):8948-52
abstractText  A PCR-based strategy for amplifying putative receptors involved in murine olfaction was employed to isolate a member (OR3) of the seven-transmembrane-domain receptor superfamily. During development, the first cells that express OR3 appear adjacent to the wall of the telencephalic vesicle at embryonic day 10. The OR3 receptor is uniquely expressed in a subset of olfactory cells that have a characteristic bilateral symmetry in the adult olfactory epithelium. This receptor and its specific pattern of expression may serve a functional role in odor coding or, alternatively, may play a role in the development of the olfactory system.
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