| First Author | Bapat B | Year | 1988 |
| Journal | FEBS Lett | Volume | 237 |
| Issue | 1-2 | Pages | 191-5 |
| PubMed ID | 2971567 | Mgi Jnum | J:9381 |
| Mgi Id | MGI:57842 | Doi | 10.1016/0014-5793(88)80199-6 |
| Citation | Bapat B, et al. (1988) Cloning and sequence analysis of a cDNA encoding the beta-subunit of mouse beta-hexosaminidase. FEBS Lett 237(1-2):191-5 |
| abstractText | A cDNA encoding the prepro-beta-polypeptide of mouse beta-hexosaminidase (Hex) was isolated from a mouse lymphoblast cDNA library. The cDNA contains an open reading frame corresponding to a polypeptide of 536 amino acids which shows 74% homology with the human prepro-beta-polypeptide. An examination of the amino acid sequence identifies a putative signal peptide and five possible glycosylation sites, two of which are identical to the confirmed glycosylation sites of the human beta-chain. The amino acid sequence also shows a structurally similar though not identical site for internal cleavage responsible for the generation of mature beta a- and beta b-polypeptides. |
