| First Author | Idusogie E | Year | 1996 |
| Journal | Thromb Haemost | Volume | 75 |
| Issue | 3 | Pages | 481-7 |
| PubMed ID | 8701412 | Mgi Jnum | J:32983 |
| Mgi Id | MGI:80471 | Citation | Idusogie E, et al. (1996) Characterization of a cDNA encoding murine coagulation factor VII. Thromb Haemost 75(3):481-7 |
| abstractText | The cDNA encoding murine coagulation factor VII (mfVII) was isolated and reconstructed from a lambda Zap cDNA library generated from murine liver mRNA. The cDNA contains 1903 nucleotides spanning 15 bases upstream of the 5'-translation initiation codon, an open reading frame of 1338 nucleotides, 550 nucleotides downstream of the first stop codon and a 3' poly(A) tail. The translation product is composed of a 41-amino acid signal/propeptide region followed by a 405-residue mature protein. The latter is highly homologous to that of human, rabbit, bovine, Rhesus monkey, and canine fVII. All protein domains of hfVII are strictly conserved in mfVII. |
