| First Author | Popsueva AE | Year | 1996 |
| Journal | FEBS Lett | Volume | 391 |
| Issue | 1-2 | Pages | 5-8 |
| PubMed ID | 8706928 | Mgi Jnum | J:34599 |
| Mgi Id | MGI:82054 | Doi | 10.1016/0014-5793(96)00692-8 |
| Citation | Popsueva AE, et al. (1996) A novel murine cathelin-like protein expressed in bone marrow. FEBS Lett 391(1-2):5-8 |
| abstractText | A novel cDNA encoding a putative secreted protein was isolated from murine bone marrow. The encoded protein named MCLP (murine cathelin-like protein) was found to be highly homologous to the pig cathelin, and to four neutrophil antimicrobial polypeptides: CAP 18, indolicidin, Bac 5 and FALL-39. Secondary structure prediction studies identified a highly cationic region in the C-terminal part of prepro-MCLP with a tendency to adopt an amphipathic alpha-helical conformation, as observed in many antimicrobial peptides. However, no antibacterial activity was observed with the synthetic peptide corresponding to this region of MCLP. |
