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Publication : Cloning and expression analysis of a novel mesodermally expressed cadherin.

First Author  Hoffmann I Year  1995
Journal  Dev Biol Volume  169
Issue  1 Pages  337-46
PubMed ID  7750649 Mgi Jnum  J:25269
Mgi Id  MGI:72994 Doi  10.1006/dbio.1995.1148
Citation  Hoffmann I, et al. (1995) Cloning and expression analysis of a novel mesodermally expressed cadherin. Dev Biol 169(1):337-46
abstractText  Cadherins are calcium-dependent cell adhesion molecules which show developmental and tissue-specific expression. Here we report the cloning of a mouse cadherin which is predominantly expressed in tissues of mesodermal origin. In contrast to other cadherins, cadherin-11 expression is largely restricted to mesenchymal tissues surrounding various organs but is not found in epithelia. Sequence analysis suggests that this cadherin is the mouse homologue of the previously reported human cadherin-11 and is a member of a cadherin subfamily, which is evolutionarily distinct from other cadherin subfamilies identified so far.
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