| First Author | Shao H | Year | 1995 |
| Journal | J Biol Chem | Volume | 270 |
| Issue | 8 | Pages | 3467-70 |
| PubMed ID | 7876076 | Mgi Jnum | J:23143 |
| Mgi Id | MGI:70930 | Doi | 10.1074/jbc.270.8.3467 |
| Citation | Shao H, et al. (1995) cDNA cloning and characterization of a Cek7 receptor protein-tyrosine kinase ligand that is identical to the ligand (ELF-1) for the Mek-4 and Sek receptor protein-tyrosine kinases. J Biol Chem 270(8):3467-70 |
| abstractText | We have isolated a murine cDNA encoding a ligand for the Cek7 receptor protein-tyrosine kinase (RPTK), a member of the Eph/Eck RPTK subfamily. Sequence analysis predicts an open reading frame of 209 amino acids with a predicted molecular mass of 24 kDa. The Cek7 ligand shows a 48% sequence identity at the protein level to B61, a ligand for the related Eck RPTK, 30% to the Cek5 ligand, 59% to the recently cloned Ehk1-L, and identity to ELF-1, a recently described ligand for the Mek4 and Sek RPTKs. The expressed Cek7 ligand is functionally active as it induces autophosphorylation of the Cek7 RPTK. |
